Which substance causes a euphoric high, feelings of intense elation, or pleasure?

The substance that is known to cause a euphoric high, along with feelings of intense elation or pleasure, is methamphetamine. Methamphetamine significantly increases the release of dopamine, a neurotransmitter that plays a key role in the brain’s reward system, leading to heightened feelings of joy and well-being. This intense release of dopamine can lead to a rapid and powerful euphoric experience, distinguishing it from other substances.

While cocaine also produces similar euphoric effects by increasing dopamine levels, methamphetamine has a longer-lasting impact on the brain's chemistry and often leads to a more intense and prolonged high. Alcohol, while capable of producing feelings of euphoria, does so through a different mechanism and generally has a more sedative effect rather than a stimulant one. Nicotine, though it can produce mild euphoria, primarily acts as a stimulant and does not create the same level of intense elation associated with methamphetamine. Therefore, among the choices provided, methamphetamine best fits the description of the substance that elicits a euphoric high and feelings of intense pleasure.